A Crisis of Infection

It’s amazing what humankind can achieve with the right amount of political will and resources. After the attack on Pearl Harbor in December 1941, Roosevelt oversaw the rebuilding of the Pacific fleet in only 6-months. Driven by rivalry with the Soviet Union, Kennedy announced in May 1961, “…we choose to go to the moon …”Continue reading “A Crisis of Infection”

New Covid-19 tests

A Covid-19 blog post for the non-expert We’ve been hearing how the UK government wants to return to normal life under its £100bn Operation Moonshot Covid-19 testing programme. Headlines such as those in the Daily Mail have proclaimed “Prospect’ of 10-minute ‘rapid turnaround’ Covid tests” but others including the BMJ are not so sure. I thought,Continue reading “New Covid-19 tests”

What is interferon and is it effective against Covid-19?

A blog post for the non-expert Our best hope against Covid-19 is an effective vaccine, and efforts in that direction are galloping along like no other time in history. There are so many vaccines being investigated, it’s hard to keep up with the numbers, but at the time of writing there appear to be wellContinue reading “What is interferon and is it effective against Covid-19?”

A sober look at dexamethasone

A Covid-19 blog post for the non-expert It stared with a 16th June 2020 press release  from the University of Oxford “Low-cost dexamethasone reduce death by up to one third in hospitalised patients with severe respiratory complications of COVID-19” – which triggered the equivalent of a media cytokine storm (pun explained shortly). I do not want,Continue reading “A sober look at dexamethasone”

Covid-19 vaccine pessimism

Another blog on Covid-19 for the non-expert I’ve seen claims on social media and in the press saying a vaccine for Covid-19 may never arrive. The Telegraph, and The Guardian are two examples. The three most commonly quoted reasons I’ve seen for vaccine pessimism are: (1) vaccines take many years to make, the mumps vaccineContinue reading “Covid-19 vaccine pessimism”

Covid-19 – warnings ignored

I’ve heard it said, we have not experienced a pandemic since the Spanish flu of 1918 so how could anyone predict Covid-19? Just about everything in that statement is wrong. Everyone has heard of Spanish flu, but how many have heard of the 1957 flu pandemic, or the one in 1968? We see an annualContinue reading “Covid-19 – warnings ignored”

What is Remdesivir and how does it work?

Another Covid-19 blog post for the non-expert. Parts of the media are claiming a drug called remdesivir has arrived to save us The BBC: “Remdesivir: Drug has ‘clear-cut’ power to fight coronavirus” RFI – Radio France Internationale, live news: “US claims major breakthrough after positive trial of coronavirus drug remdesivir” The Express: “Hope of coronavirusContinue reading “What is Remdesivir and how does it work?”

Covid-19 and blood pressure

As well as a vaccine, studies are being conducted into drugs which might stop, or at least inhibit, the effects of the SARS-CoV-2 virus. Modern drugs are designed to target specific sites, called receptors, in the body and the right choice of receptor is often the difference between a successful drug and a dud. IContinue reading “Covid-19 and blood pressure”

What is herd immunity?

We’ve all heard a lot recently about herd immunity (pun intended), but it’s a term which seems to cause a lot of confusion. First off, let me tell you what it’s not. It’s not about a population becoming exposed to the Covid-19 virus and those with some resistance or those being “fitter” surviving while othersContinue reading “What is herd immunity?”